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Freshly updated: January 17, 2025

Best Boutique Hotels in Panama CityBest Boutique Hotels in Panama City

Welcome to Panama City, a place where glitzy skyscrapers tower over colonial-era plazas, and the buzz of urban life collides with the tranquility of tropical beauty. When it comes to accommodations, the best boutique hotels in Panama City don’t just offer a place to rest, they deliver an experience! From personalized service to thoughtfully designed spaces, these hotels are your gateway to discovering the city in style.

You can start your day with a rooftop breakfast overlooking the iconic skyline, or wandering through the cobbled streets of Casco Viejo. Each hotel is uniquely designed to match the city’s vibrant personality, combining luxury with the charm of a more intimate setting.

What Makes a Boutique Hotel in Panama City Stand Out?

  • Thoughtful Design: Wave goodbye to generic interiors! Each boutique hotel boasts a unique aesthetic. Think artfully restored colonial buildings or contemporary spaces filled with Panamanian design flair.
  • Exceptional Service: Staff go above and beyond, offering a personalized experience that larger hotels can’t match.
  • Prime Locations: Many are nestled in Casco Viejo or along the waterfront, putting you steps away from the city’s top attractions.
  • Exclusive Amenities: Beyond the deluxe beds and stylish bathrooms, boutique hotels offer curated experiences. Picture rooftop yoga overlooking the cityscape, private cooking classes, or exclusive access to cultural events.

How to Book Hotels in Panama City

You will find in this guide direct links to the biggest hotel booking portal in the world, Booking.com.

Booking.com is the safest way to book your hotel! Once you complete the reservation, you will receive a confirmation email. It’s very simple to use!

Here is our handwritten review on how to use Booking.com.

All Boutique Hotels in Panama City in Detail

Forget the hunt – we’ve done the legwork! These handpicked boutique hotels in Panama City are sure to elevate your stay and make your trip memorable.

Amarla Boutique Hotel Casco Viejo

Craving a luxury escape in Panama? They say luxury is personal, and Amarla Boutique Hotel in Casco Viejo proves it. Each room is a sanctuary, you can expect free Wi-Fi, room service, airport shuttle, excellent breakfast, and artisanal decoration that speaks of Panama’s vibrant culture.

Amarla also offers a rooftop pool with breathtaking views of the city skyline and the Panama Bay, a perfect spot for sunset cocktails. Want a serene spot for relaxation? That’s the garden, it’s ideal for a quiet morning coffee or an evening of relaxation under the stars.

Dining here is a sensory experience. The hotel’s restaurant serves exquisite dishes crafted from fresh, locally sourced ingredients, while the bar offers a curated selection of wines and signature cocktails.

What about the Location?

Amarla’s location is a treasure in itself. Situated in the heart of Casco Viejo, you’re just steps away from vibrant plazas, artisanal shops, and some of the city’s best restaurants and nightlife.

Amarla Boutique Hotel Casco Viejo is one of the best boutique hotels in Panama City Casco Viejo. The exact address is
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Booking.com is the best site for hotel reservations. Read more reviews at Booking.com here.

Total number of rooms: 8 | Prices start from US$

Read our full Review of Amarla Boutique Hotel Casco Viejo

Hotel La Compania, In The Unbound Collection By Hyatt

Welcome to Hotel La Compañía – by Hyatt. This place is more than a stay; it’s an experience. Housed in restored buildings dating back to the 17th century, this boutique gem celebrates the city’s rich heritage while embracing contemporary luxury.

Each room tells a story, with unique decor reflecting Spanish, French, or American colonial styles. Modern travelers will appreciate amenities like high-speed Wi-Fi, flat-screen TVs, and cozy beds. The hotel boasts three on-site restaurants, offering everything from fine dining to casual bites, as well as a rooftop bar that provides panoramic views of the Casco Viejo skyline. Perfect for a romantic evening or a sunset cocktail.

But there’s more, you can take a dip in the outdoor pool, surrounded by gardens, or pamper yourself at the hotel’s world-class spa. Are you a fitness enthusiast? You will love gym here!

What about the Location?

Hotel La Compania, In The Unbound Collection By Hyatt is one of the best boutique hotels in Panama City Casco Viejo. The exact address is
.

Booking.com is the best site for hotel reservations. Read more reviews at Booking.com here.

Total number of rooms: 85 | Prices start from 572 US$

Read our full Review of Hotel La Compania, In The Unbound Collection By Hyatt

La Concordia – Boutique Hotel

Luxury is in each detail, or so they say at La Concordia – Boutique Hotel. And let me tell you, it’s hard to disagree. With only a handful of tastefully designed rooms, this boutique gem offers an intimate experience. From the moment you walk in, you’re surrounded by an inviting mix of classic architecture and contemporary flair.

The hotel’s amenities cater to the modern traveler. Free high-speed Wi-Fi keeps you connected, while the on-site rooftop bar offers the perfect setting to disconnect. Sip a craft cocktail as you take in panoramic views of the city’s iconic skyline and Casco Viejo’s cobblestone streets.

The rooms at La Concordia are a sanctuary. With comfy bedding, rainfall showers, and balconies that open to the lively streets below or serene courtyards. Want to be pampered? The personalized service extends to every corner, whether you’re asking for sightseeing tips or indulging in room service.

Good to know: The hotel’s boutique size ensures a quiet and exclusive vibe, making it ideal for those seeking a more personalized stay.

What about the Location?

La Concordia – Boutique Hotel is one of the best boutique hotels in Panama City Casco Viejo. The exact address is
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Booking.com is the best site for hotel reservations. Read more reviews at Booking.com here.

Total number of rooms: 11 | Prices start from US$

Read our full Review of La Concordia – Boutique Hotel

Las Clementinas

Looking for a charming stay in the heart of Panama City? You’re in for a treat! Las Clementinas is located in Casco Viejo. The hotel combines history with modern comfort offering massage services, free Wi-Fi, airport shuttle service, and, of course, two fantastic on-site restaurants to delight every palate.

Craving relaxation? Unwind on the furnished terrace, where you can soak in stunning city skyline views, or find peace in the lush tropical garden, a perfect escape to melt your stress away.

Its Queen Suites exude casual luxury, blending contemporary décor with historic charm. Picture this: tall ceilings, cozy living areas, and large windows that frame stunning views of Panama City. Whether you’re relaxing in your spacious suite or cooking up a quick meal in the fully-equipped kitchen, every detail feels like home, but elevated.

What about the Location?

The location of Las Clementinas is absolutely exceptional. A short five-minute stroll will take you to the picturesque seafront boulevard, perfect for sunset walks. For those seeking vibrant dining and entertainment options, the Cosway Zone is just a ten-minute drive away. And with Tocumen International Airport only 20 minutes from your doorstep, convenience is always on your side.

Las Clementinas is one of the best boutique hotels in Panama City Casco Viejo. The exact address is
.

Booking.com is the best site for hotel reservations. Read more reviews at Booking.com here.

Total number of rooms: 9 | Prices start from 157.3 US$

Read our full Review of Las Clementinas

American Trade Hotel

History is made at night, or so they say at the American Trade Hotel. This place is a masterpiece of heritage and contemporary design, offering guests a glimpse into Panama City’s past while indulging them in modern luxuries. The hotel is Housed in a restored historic building, with spacious rooms featuring hardwood floors, high ceilings, and artisanal touches, the hotel is elegant yet modern.

The hotel offers something special at every turn, like delicious coffee from their award-winning café or and handcrafted cocktails at the Jazz Club, a beloved venue that attracts world-class performers. The on-site restaurant presents a curated menu celebrating local and international flavors, paired with an exceptional wine selection.

What else? Guests can also take a refreshing dip in the outdoor pool or work out in the fitness center, all while enjoying views of the picturesque city skyline.

What about the Location?

Nestled in the heart of Casco Viejo, the historic district of Panama City, you'll be steps away from cobblestone streets, colorful colonial architecture, and bustling plazas.

American Trade Hotel is one of the best boutique hotels in Panama City Casco Viejo. The exact address is
.

Booking.com is the best site for hotel reservations. Read more reviews at Booking.com here.

Total number of rooms: 50 | Prices start from US$

Read our full Review of American Trade Hotel

Global Hotel Panama

Cosmopolitan chic and Panamanian warmth? That’s what you find at Global Hotel Panama. Offering luxurious amenities like high-speed Wi-Fi, a rooftop pool with stunning city views, and plush rooms featuring floor-to-ceiling windows, this boutique gem ensures a memorable stay. The rooms are havens of tranquility, featuring plush bedding, nice amenities, and stunning city views. People especially love the floor-to-ceiling windows. They let in so much natural light!

Start your mornings with a delectable breakfast at their in-house restaurant, serving a mix of international and local flavors. Wind down in the evening at the bar, their cocktails set the perfect tone for your night.

Want to stay active? The hotel has a gym. Prefer pampering? They have the best spa on-site.

Good to know: The hotel offers valet parking and 24-hour concierge services to make your stay completely hassle-free.

What about the Location?

Located in the vibrant Obarrio neighborhood, the hotel is at the heart of Panama City’s financial and cultural district, Bellavista. You’re just minutes away from upscale shopping, fine dining, and iconic landmarks.

Global Hotel Panama is one of the best boutique hotels in Panama City Obarrio neighborhood. The exact address is
.

Booking.com is the best site for hotel reservations. Read more reviews at Booking.com here.

Total number of rooms: 60 | Prices start from 138.6 US$

Read our full Review of Global Hotel Panama

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